Monday, April 29, 2013

Bombing suspects' mother draws heavy scrutiny

BOSTON (AP) ? In photos of her as a younger woman, Zubeidat Tsarnaeva wears a low-cut blouse and has her hair teased like a 1980s rock star. After she arrived in the U.S. from Russia in 2002, she went to beauty school and did facials at a suburban day spa.

But in recent years, people noticed a change. She began wearing a hijab and cited conspiracy theories about 9/11 being a plot against Muslims.

Now known as the angry and grieving mother of the Boston Marathon bombing suspects, Tsarnaeva is drawing increased attention after federal officials say Russian authorities intercepted her phone calls, including one in which she vaguely discussed jihad with her elder son. In another, she was recorded talking to someone in southern Russia who is under FBI investigation in an unrelated case, U.S. officials said.

Tsarnaeva insists there is no mystery. She's no terrorist, just someone who found a deeper spirituality. She insists her sons ? Tamerlan, who was killed in a gunfight with police, and Dzhokhar, who was wounded and captured ? are innocent.

"It's all lies and hypocrisy," she told The Associated Press in Dagestan. "I'm sick and tired of all this nonsense that they make up about me and my children. People know me as a regular person, and I've never been mixed up in any criminal intentions, especially any linked to terrorism."

Amid the scrutiny, Tsarnaeva and her ex-husband, Anzor Tsarnaev, say they have put off the idea of any trip to the U.S. to reclaim their elder son's body or try to visit Dzhokhar in jail. Tsarnaev told the AP on Sunday he was too ill to travel to the U.S. Tsarnaeva faces a 2012 shoplifting charge in a Boston suburb, though it was unclear whether that was a deterrent.

At a news conference in Dagestan with Anzor last week, Tsarnaeva appeared overwhelmed with grief one moment, defiant the next. "They already are talking about that we are terrorists, I am terrorist," she said. "They already want me, him and all of us to look (like) terrorists."

Tsarnaeva arrived in the U.S. in 2002, settling in a working-class section of Cambridge, Mass. With four children, Anzor and Zubeidat qualified for food stamps and were on and off public assistance benefits for years. The large family squeezed itself into a third-floor apartment.

Zubeidat took classes at the Catherine Hinds Institute of Esthetics, before becoming a state-licensed aesthetician. Anzor, who had studied law, fixed cars.

By some accounts, the family was tolerant.

Bethany Smith, a New Yorker who befriended Zubeidat's two daughters, said in an interview with Newsday that when she stayed with the family for a month in 2008 while she looked at colleges, she was welcomed even though she was Christian and had tattoos.

"I had nothing but love over there. They accepted me for who I was," Smith told the newspaper. "Their mother, Zubeidat, she considered me to be a part of the family. She called me her third daughter."

Zubeidat said she and Tamerlan began to turn more deeply into their Muslim faith about five years ago after being influenced by a family friend, named "Misha." The man, whose full name she didn't reveal, impressed her with a religious devotion that was far greater than her own, even though he was an ethnic Armenian who converted to Islam.

"I wasn't praying until he prayed in our house, so I just got really ashamed that I am not praying, being a Muslim, being born Muslim. I am not praying. Misha, who converted, was praying," she said.

By then, she had left her job at the day spa and was giving facials in her apartment. One client, Alyssa Kilzer, noticed the change when Tsarnaeva put on a head scarf before leaving the apartment.

"She had never worn a hijab while working at the spa previously, or inside the house, and I was really surprised," Kilzer wrote in a post on her blog. "She started to refuse to see boys that had gone through puberty, as she had consulted a religious figure and he had told her it was sacrilegious. She was often fasting."

Kilzer wrote that Tsarnaeva was a loving and supportive mother, and she felt sympathy for her plight after the April 15 bombings. But she stopped visiting the family's home for spa treatments in late 2011 or early 2012 when, during one session, she "started quoting a conspiracy theory, telling me that she thought 9/11 was purposefully created by the American government to make America hate Muslims."

"It's real," Tsarnaeva said, according to Kilzer. "My son knows all about it. You can read on the Internet."

In the spring of 2010, Zubeidat's eldest son got married in a ceremony at a Boston mosque that no one in the family had previously attended. Tamerlan and his wife, Katherine Russell, a Rhode Island native and convert from Christianity, now have a child who is about 3 years old.

Zubeidat married into a Chechen family but was an outsider. She is an Avar, from one of the dozens of ethnic groups in Dagestan. Her native village is now a hotbed of an ultraconservative strain of Islam known as Salafism or Wahabbism.

It is unclear whether religious differences fueled tension in their family. Anzor and Zubeidat divorced in 2011.

About the same time, there was a brief FBI investigation into Tamerlan Tsarnaev, prompted by a tip from Russia's security service.

The vague warning from the Russians was that Tamerlan, an amateur boxer in the U.S., was a follower of radical Islam who had changed drastically since 2010. That led the FBI to interview Tamerlan at the family's home in Cambridge. Officials ultimately placed his name, and his mother's name, on various watch lists, but the inquiry was closed in late spring of 2011.

After the bombings, Russian authorities told U.S. investigators they had secretly recorded a phone conversation in which Zubeidat had vaguely discussed jihad with Tamerlan. The Russians also recorded Zubeidat talking to someone in southern Russia who is under FBI investigation in an unrelated case, according to U.S. officials who spoke on condition of anonymity because they were not authorized to discuss the investigation with reporters.

The conversations are significant because, had they been revealed earlier, they might have been enough evidence for the FBI to initiate a more thorough investigation of the Tsarnaev family.

Anzor's brother, Ruslan Tsarni, told the AP from his home in Maryland that he believed his former sister-in-law had a "big-time influence" on her older son's growing embrace of his Muslim faith and decision to quit boxing and school.

While Tamerlan was living in Russia for six months in 2012, Zubeidat, who had remained in the U.S., was arrested at a shopping mall in the suburb of Natick, Mass., and accused of trying to shoplift $1,624 worth of women's clothing from a department store.

She failed to appear in court to answer the charges that fall, and instead left the country.

___

Seddon reported from Makhachkala, Russia. Associated Press writers Eileen Sullivan and Matt Apuzzo contributed to this report from Washington.

Source: http://news.yahoo.com/mother-bomb-suspects-found-deeper-spirituality-224317582.html

nikki minaj grammy performance shel silverstein niki minaj grammy performance grammys 2012 deadmau5 phoebe snow jennifer hudson tribute to whitney houston

Saturday, April 27, 2013

How To Lose The Sequestration Fight (talking-points-memo)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/301781550?client_source=feed&format=rss

Closing Ceremony London 2012 Tom Daley Leryn Franco The Campaign Kinesio tape randy travis Allyson Felix

Samsung's official Q1 earnings show $6.4 billion in net profit

Samsung Electronics has released its Q1 2013 numbers and as it predicted a few weeks ago, business continues to boom. Operating profits are 8.78 trillion won as predicted, while net profit is up to 7.15 trillion won ($6.4 billion), up sharply from the same quarter last year when its net profit was 5.50 trillion won. Last year at this time we were still anticipating details on the Galaxy S III, but this time around Samsung is on the eve of its worldwide launch for the Galaxy S 4, which should push sales even higher. According to the documents, it's maintained a "steady pace" for Galaxy S III sales, while Note II sales increased and the Tab2 series increased momentum. The news isn't as good for PCs, shipments decreased due to weak demand. earnings in its TV business were also down from last quarter, blamed on the same lower overall market demand noted by LG in its earnings. We're listening in on the earnings call now, we'll have more information on just how it made all that cash (hint: lots of Galaxy phones) in a moment.

Developing...

Filed under: , , , ,

Comments

Source: Yonhap, Bloomberg, Reuters, Samsung (PDF)

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/pkQygMFhJoo/

lollapalooza lineup joss whedon ronnie montrose melissa gilbert dancing with the stars dandelion wine cough matt groening

Arkansas group plans meeting on Exxon oil spill

MAYFLOWER, Ark. (AP) -- A group that's critical of the oil spill in central Arkansas from an Exxon Mobil Corp. pipeline is holding a meeting to mark the one-month anniversary of the accident.

The group Arkansans Concerned about Oil Pipelines is to gather at 6 p.m. Monday at Pearce Park in Mayflower.

Thousands of gallons of oil spilled into a cove off Lake Conway and more than 20 homes had to be evacuated.

Environmental testing has shown no oil has leaked into Lake Conway, but hazardous fumes have been registered in the evacuated area, where the cleanup continues.

Source: http://news.yahoo.com/arkansas-group-plans-meeting-exxon-161305931.html

guild wars 2 adrian gonzalez Jerry Nelson Foo Canoodle Isaac path Tropical Storm Isaac path

Friday, April 26, 2013

Missing link in Parkinson's disease found: Discovery also has implications for heart failure

Apr. 25, 2013 ? Researchers at Washington University School of Medicine in St. Louis have described a missing link in understanding how damage to the body's cellular power plants leads to Parkinson's disease and, perhaps surprisingly, to some forms of heart failure.

These cellular power plants are called mitochondria. They manufacture the energy the cell requires to perform its many duties. And while heart and brain tissue may seem entirely different in form and function, one vital characteristic they share is a massive need for fuel.

Working in mouse and fruit fly hearts, the researchers found that a protein known as mitofusin 2 (Mfn2) is the long-sought missing link in the chain of events that control mitochondrial quality.

The findings are reported April 26 in the journal Science.

The new discovery in heart cells provides some explanation for the long known epidemiologic link between Parkinson's disease and heart failure.

"If you have Parkinson's disease, you have a more than two-fold increased risk of developing heart failure and a 50 percent higher risk of dying from heart failure," says senior author Gerald W. Dorn II, MD, the Philip and Sima K. Needleman Professor of Medicine. "This suggested they are somehow related, and now we have identified a fundamental mechanism that links the two."

Heart muscle cells and neurons in the brain have huge numbers of mitochondria that must be tightly monitored. If bad mitochondria are allowed to build up, not only do they stop making fuel, they begin consuming it and produce molecules that damage the cell. This damage eventually can lead to Parkinson's or heart failure, depending on the organ affected. Most of the time, quality-control systems in a healthy cell make sure damaged or dysfunctional mitochondria are identified and removed.

Over the past 15 years, scientists have described much of this quality-control system. Both the beginning and end of the chain of events are well understood. And since 2006, scientists have been working to identify the mysterious middle section of the chain -- the part that allows the internal environment of sick mitochondria to communicate to the rest of the cell that it needs to be destroyed.

"This was a big question," Dorn says. "Scientists would draw the middle part of the chain as a black box. How do these self-destruct signals inside the mitochondria communicate with proteins far away in the surrounding cell that orchestrate the actual destruction?"

"To my knowledge, no one has connected an Mfn2 mutation to Parkinson's disease," Dorn says. "And until recently, I don't think anybody would have looked. This isn't what Mfn2 is supposed to do."

Mitofusin 2 is known for its role in fusing mitochondria together, so they might exchange mitochondrial DNA in a primitive form of sexual reproduction.

"Mitofusins look like little Velcro loops," Dorn says. "They help fuse together the outer membranes of mitochondria. Mitofusins 1 and 2 do pretty much the same thing in terms of mitochondrial fusion. What we have done is describe an entirely new function for Mfn2."

The mitochondrial quality-control system begins with what Dorn calls a "dead man's switch."

"If the mitochondria are alive, they have to do work to keep the switch depressed to prevent their own self-destruction," Dorn says.

Specifically, mitochondria work to import a molecule called PINK. Then they work to destroy it. When mitochondria get sick, they can't destroy PINK and its levels begin to rise. Then comes the missing link that Dorn and his colleague Yun Chen, PhD, senior scientist, identified. Once PINK levels get high enough, they make a chemical change to Mfn2, which sits on the surface of mitochondria. This chemical change is called phosphorylation. Phosphorylated Mfn2 on the surface of the mitochondria can then bind with a molecule called Parkin that floats around in the surrounding cell.

Once Parkin binds to Mfn2 on sick mitochondria, Parkin labels the mitochondria for destruction. The labels then attract special compartments in the cell that "eat" and destroy the sick mitochondria. As long as all links in the quality-control system work properly, the cells' damaged power plants are removed, clearing the way for healthy ones.

"But if you have a mutation in PINK, you get Parkinson's disease," Dorn says. "And if you have a mutation in Parkin, you get Parkinson's disease. About 10 percent of Parkinson's disease is attributed to these or other mutations that have been identified."

According to Dorn, the discovery of Mfn2's relationship to PINK and Parkin opens the doors to a new genetic form of Parkinson's disease. And it may help improve diagnosis for both Parkinson's disease and heart failure.

"I think researchers will look closely at inherited Parkinson's cases that are not explained by known mutations," Dorn says. "They will look for loss of function mutations in Mfn2, and I think they are likely to find some."

Similarly, as a cardiologist, Dorn and his colleagues already have detected mutations in Mfn2 that appear to explain certain familial forms of heart failure, the gradual deterioration of heart muscle that impairs blood flow to the body. He speculates that looking for mutations in PINK and Parkin might be worthwhile in heart failure as well.

"In this case, the heart has informed us about Parkinson's disease, but we may have also described a Parkinson's disease analogy in the heart," he says. "This entire process of mitochondrial quality control is a relatively small field for heart specialists, but interest is growing."

This work was supported by the National Institutes of Health (NIH) grants R01 HL059888 and R21 HL107276.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Washington University School of Medicine. The original article was written by Julia Evangelou Strait.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Y. Chen, G. W. Dorn. PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria. Science, 2013; 340 (6131): 471 DOI: 10.1126/science.1231031

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/QSYvGCfVQ78/130425142357.htm

stacy keibler oscar red carpet daytona 500 start time ryan zimmerman oscars red carpet jennifer lopez wardrobe malfunction hugo

Thursday, April 25, 2013

Justice says Armstrong was 'unjustly enriched'

FILE - In this Feb. 15, 2011 file photo, Lance Armstrong pauses during an interview in Austin, Texas. The Justice Department laid out its case in a lawsuit against Lance Armstrong on Tuesday, Apriil 23, 2013 saying the cyclist violated his contract with the U.S. Postal Service and was "unjustly enriched" while cheating to win the Tour de France. (AP Photo/Thao Nguyen, File)

FILE - In this Feb. 15, 2011 file photo, Lance Armstrong pauses during an interview in Austin, Texas. The Justice Department laid out its case in a lawsuit against Lance Armstrong on Tuesday, Apriil 23, 2013 saying the cyclist violated his contract with the U.S. Postal Service and was "unjustly enriched" while cheating to win the Tour de France. (AP Photo/Thao Nguyen, File)

(AP) ? The federal government is going after Lance Armstrong's money. As much as it can get.

The Justice Department unveiled its formal complaint against Armstrong on Tuesday, saying the cyclist violated his contract with the U.S. Postal Service and was "unjustly enriched" while cheating to win the Tour de France.

The government had previously announced it would join a whistle-blower lawsuit brought by former Armstrong teammate Floyd Landis under the federal False Claims Act. Tuesday was the deadline to file its formal complaint.

The Postal Service paid about $40 million to be the title sponsor of Armstrong's teams for six of his seven Tour de France victories. The filing in U.S. district court in Washington, D.C., says the USPS paid Armstrong $17 million from 1998-2004.

The lawsuit also names former team Armstrong team director Johan Bruyneel and team management company Tailwind Sports as defendants.

"Defendants were unjustly enriched to the extent of the payments and other benefits they received from the USPS, either directly or indirectly," the complaint said.

The financial costs for Armstrong and Bruyneel could be high. The government said it would seek triple damages assessed by the jury. Armstrong has been dropped by his personal sponsors and left the cancer-fighting foundation he started in 1997.

Armstrong had previously tried to negotiate a settlement, but those talks fell through before the government announced it would join the Landis lawsuit. Settlement talks could resume as the case proceeds to trial.

Armstrong, who in January admitted using performance-enhancing drugs after years of denials, has argued that the Postal Service's endorsement of his team earned the government agency far more than it paid him.

Armstrong attorney Elliot Peters called the government's complaint "opportunistic" and "insincere."

"The U.S. Postal Service benefited tremendously from its sponsorship of the cycling team. Its own studies repeatedly and conclusively prove this," Peters said. "The USPS was never the victim of fraud. Lance Armstrong rode his heart out for the USPS team, and gave the brand tremendous exposure during the sponsorship years."

The government must prove not only that the Postal Service was defrauded, but that it was damaged somehow.

Previous studies done for the Postal Service concluded the agency reaped at least $139 million in worldwide brand exposure in four years ? $35 million to $40 million for sponsoring the Armstrong team in 2001; $38 million to $42 million in 2002; $31 million in 2003; and $34.6 million in 2004.

Landis attorney Paul Scott dismissed the idea that money gained by the Postal Service should negate the claims of fraud. Scott the Postal Service is tainted by the drug scandal.

"Even if the USPS received some ephemeral media exposure in connection with Mr. Armstrong's false victories, any illusory benefit from those times will be swamped over time immemorial by the USPS forever being tied to the largest doping scandal in the history of sports," Scott said.

The formal complaint against Armstrong appears to rely heavily on evidence and statements supplied by Landis and gathered by the U.S. Anti-Doping Agency for its 2012 investigation that exposed a doping program on the USPS team. Armstrong has been banned from sports for life and stripped of his seven Tour de France victories.

As Armstrong's teammate, Landis participated in the doping program. He was later stripped of his 2006 Tour de France title won with another team because of his own doping violations.

Bruyneel, who lives in London, also has been charged by USADA with doping violations but is fighting that case in arbitration.

The government notes the contract with the Postal Service required riders to follow the rules of cycling, which included bans on performance-enhancing drugs and methods. Armstrong now admits using steroids, blood boosters and other illegal performance-enhancing drugs and measures to win.

By breaking the rules and covering it up, Armstrong and Bruyneel committed fraud against the U.S. government, the complaint said.

The complaint said that for years, team officials assured the Postal Service that the team wasn't doping.

Armstrong had been the target of a federal criminal grand jury, but that case was closed without charges in February 2012. Armstrong has previously tried to settle the Landis whistleblower lawsuit, but those talks broke down before the government announced its intention to join the case.

Armstrong also is fighting a lawsuit from Dallas-based promotions company SCA to recover about $12 million it paid him in bonuses, and a lawsuit from the London-based Sunday Times, which wants to get back $500,000 it paid him to settle a libel case.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-04-24-Armstrong-Doping/id-c6b2f65587f945bbb05be66447326adf

edwin jackson punksatony phil 2012 groundhog day groundhog phil pee wee herman ketamine ground hogs day 2012

Tuesday, March 12, 2013

Forensics firm to cut 170 jobs

A forensics firm is axing up to 170 jobs after "unprecedented change" in the market, it has said.

LGC, which has worked on the cases of Rachel Nickell and Damilola Taylor, is based in Teddington, Middlesex, but has laboratories across the world.

The losses will come from the eight UK sites. Of the 200 posts in Culham, Oxfordshire, half are being reviewed.

Spokeswoman Guenaelle Holloway said LGC would be "streamlined and simplified" to make it more cost-effective.

LGC's turnover was ?168m in 2011-2012, but following an increased workload after the announced closure of the Forensic Science Service in 2010, it says the market has "normalised".

'Realigning business'

Ms Holloway said: "The change programme will focus LGC on fewer specialist sites, creating bigger, more flexible teams; reshape our team structures to meet the skills mix required by changing customer needs; and reduce the total workforce by approximately 150-170 full-time employees.

"For those employees whose jobs may be at risk, this will be a difficult time.

Continue reading the main story

DNA analysis

  • DNA carries our genetic code and determines traits from eye colour to personality
  • The 0.1% of DNA code sequences that vary from person to person are what make us unique
  • These are called genetic markers and are the part of the code that scientists use for DNA analysis

"We will fully support them as we realign the business, and do our utmost to help them secure new positions.

"This change programme is a critical part of LGC's commitment to building a robust and market-leading business for the long term."

LGC employs 1,800 staff in 22 countries.

The firm, which is the largest forensic science service provider in the UK, has the statutory function of Government Chemist.

As such, it provides advice to government and industry, acting as the referee analyst in cases of dispute.

It has played the role for more than 100 years, and before privatisation in 1996 it was known as the Laboratory of the Government Chemist.

LGC's UK laboratories are in Culham, Leeds, Runcorn in Cheshire, St Neots in Cambridgeshire, Tamworth in Staffordshire, Teddington, Risley in Cheshire, and Wakefield in West Yorkshire.

Some employees have taken voluntary redundancy or agreed to be relocated to other premises. A 90-day consultation is being held.

Horsemeat

LGC estimates the size of the forensics market, outside the work police do themselves, fell from roughly ?155m in 2010 to ?70-80m in 2012.

It recently worked on evidence for the trial of nine men accused of grooming and exploiting girls for sex in Oxford.

It also worked on the Vikki Thompson murder trial, in which Mark Weston became the first person to face a second murder trial after new DNA evidence came to light.

Away from crime, LGC also offers meat species testing, such as detecting the presence of horsemeat in food products.

Source: http://www.bbc.co.uk/news/uk-england-21744388#sa-ns_mchannel=rss&ns_source=PublicRSS20-sa

jane russell meryl streep martin scorsese sacha baron cohen best picture nominees 2012 academy awards 2012 albert nobbs